FTL Antibody / Ferritin light chain orb386089 from Biorbyt

Description

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts

Product Specs
ItemFTL Antibody / Ferritin light chain
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb386089
Quantity20 µg, 100 µg
ApplicationsELISA, IHC-P, WB
Conjugate/TagUnconjugated
PurityProtein G Affinity Chromatography
ReactivityHuman
TargetFTL
IsotypeMouse IgG2b, kappa
CloneFTL/1386
HostMouse
ImmunogenAmino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody
NCBI Full Gene Nameferritin light chain
NCBI Gene AliasesLFTD, NBIA3
ClonalityMonoclonal
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
StorageStore the Ferritin Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide)

Specifications/Features

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ferritin Light Chain antibody to be titered up or down for optimal performance.

Application Dilutions: ELISA: order BSA/sodium azide-free format for coating,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.25-0.5ug/ml

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